Gaseous Exchange in Humans – 25 Most Important MCQs with Answers

Preparing for MDCAT, PPSC, and other competitive exams? Here are the 25 most repeated MCQs on Gaseous Exchange in Humans with correct answers to help you revise quickly.


MCQs on Gaseous Exchange in Humans

1. Site of gaseous exchange in human lungs is:
A) Bronchi
B) Bronchioles
C) Alveoli ✅
D) Trachea

2. Which structure increases the surface area for gaseous exchange?
A) Alveoli ✅
B) Bronchi
C) Pleura
D) Diaphragm

3. Main muscle involved in inspiration is:
A) Diaphragm ✅
B) Intercostal muscles
C) Abdominal muscles
D) Sternum

4. Oxygen transport in blood is mainly through:
A) Plasma
B) Hemoglobin ✅
C) WBC
D) Platelets

5. Normal breathing rate in adults at rest is:
A) 6–8 per minute
B) 12–18 per minute ✅
C) 20–25 per minute
D) 30–35 per minute

6. The process of taking in oxygen and releasing carbon dioxide is called:
A) Respiration ✅
B) Photosynthesis
C) Excretion
D) Digestion

7. Hemoglobin combines with oxygen to form:
A) Carboxyhemoglobin
B) Oxyhemoglobin ✅
C) Carbaminohemoglobin
D) Myoglobin

8. CO₂ is mainly transported in blood as:
A) Dissolved CO₂
B) Carbaminohemoglobin
C) Bicarbonate ions ✅
D) Carbonic acid

9. Exchange of gases between blood and body tissues is called:
A) Internal respiration ✅
B) External respiration
C) Cellular respiration
D) Ventilation

10. Which enzyme helps in rapid conversion of CO₂ into bicarbonate in RBCs?
A) Amylase
B) Carbonic anhydrase ✅
C) Lipase
D) Pepsin

11. Which part of brain controls breathing?
A) Cerebrum
B) Medulla oblongata ✅
C) Cerebellum
D) Hypothalamus

12. Inspiration occurs when diaphragm:
A) Relaxes
B) Contracts ✅
C) Becomes rigid
D) Moves upward

13. Which of the following decreases during expiration?
A) Lung volume ✅
B) Pressure in lungs
C) Air pushed out
D) Alveolar recoil

14. Partial pressure of oxygen in alveoli is about:
A) 40 mmHg
B) 100 mmHg ✅
C) 140 mmHg
D) 200 mmHg

15. Total surface area of alveoli in human lungs is approximately:
A) 5 m²
B) 50 m²
C) 70 m² ✅
D) 200 m²

16. Respiratory pigment in humans is:
A) Hemocyanin
B) Hemoglobin ✅
C) Myoglobin
D) Chlorophyll

17. Pneumonia primarily affects:
A) Alveoli ✅
B) Trachea
C) Pleura
D) Diaphragm

18. Oxygen dissociation curve of hemoglobin is:
A) Linear
B) Sigmoid (S-shaped) ✅
C) Exponential
D) Hyperbolic

19. Which factor decreases affinity of hemoglobin for oxygen?
A) Low temperature
B) High CO₂ concentration ✅
C) Low H⁺ concentration
D) Low 2,3-BPG

20. Normal tidal volume in adult humans is:
A) 100 ml
B) 300 ml
C) 500 ml ✅
D) 1500 ml

21. Which structure prevents food from entering trachea during swallowing?
A) Glottis
B) Epiglottis ✅
C) Larynx
D) Uvula

22. Which gas has the highest diffusion rate?
A) O₂
B) CO₂ ✅
C) N₂
D) H₂

23. Hyperventilation leads to:
A) Increase in CO₂ in blood
B) Decrease in CO₂ in blood ✅
C) Increase in O₂ in blood
D) No effect

24. Which condition results from deficiency of surfactant in lungs?
A) Asthma
B) Emphysema
C) Respiratory distress syndrome ✅
D) Bronchitis

25. Smoking damages gaseous exchange by destroying:
A) Alveoli ✅
B) Diaphragm
C) Trachea
D) Bronchioles


✅ These MCQs are highly repeated in PPSC, MDCAT, and entry tests. Practice them well to boost you

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